Dr. Laurent Chatre, CNRS, Université de Caen Normandie, brings a systemic vision of longevity that moves beyond genes, molecules, or single pathways. His work explores how aging emerges from a progressive loss of coordination between biological systems, rather than from the failure of any isolated component.

Longevity has long been pursued as a target a gene to modify, a pathway to inhibit, a technological challenge to solve. Yet decades of intervention have delivered only modest gains, often accompanied by outsized promises. Today, the paradigm is shifting.

In this new framework, mitochondria, the microbiota, and redox signaling emerge as central regulators of adaptation and resilience over time. Their continuous dialogue shapes how organisms respond to stress, preserve coherence, and maintain function influencing resilience more than lifespan itself.

At Targeting Longevity 2026, Laurent Chatre will present a systems-level perspective on longevity, arguing that the future of the field will not lie in targeting components, but in preserving coordination and coherence within living systems as they evolve over time. His contribution aligns fully with the spirit of the meeting: rethinking aging as a dynamic, integrative process rather than a collection of disconnected mechanisms.

Targeting Longevity 2026
April 8-9, 2026
 – Berlin, Germany

www.targeting-longevity.com