Microbiota to Host Aging: The Redox Machinery as a System Integrator

Microbiota to Host Aging: The Redox Machinery as a System Integrator

Soheil Saeedi, University of Zurich, Switzerland

The dialogue between gut microbiota and host physiology is increasingly recognized as an important regulator of aging. At Targeting Longevity 2026, Soheil Saeedi will explore how redox machinery may act as a biological bridge between microbial ecosystems and host aging processes.

Recent research suggests that microbial metabolites and host metabolic signals converge on redox regulation, influencing inflammation, cellular stress responses, and tissue resilience over time. Rather than acting independently, microbiota composition and redox balance appear to form an integrated system shaping how organisms adapt during aging.

By examining this microbiota–redox–aging axis, the presentation will highlight how communication between microbial and host systems contributes to long term biological stability. Understanding this dialogue may help identify new strategies to preserve resilience during aging.

This contribution reflects the spirit of Targeting Longevity, where aging is explored as a dynamic process emerging from interactions between mitochondria, microbiota, metabolism, and cellular signaling networks.

Targeting Longevity 2026
April 8-9, 2026
 – Berlin, Germany

www.targeting-longevity.com

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